Pre Conference Workshops (£100)
Tuesday 27th January, 2015

09:00 - 12:00
Using Mechanistic Physiological Models in Drug Development: A Proven Quantitative Systems Pharmacology (QSP) Approach

In this workshop, you will learn what mechanistic physiological QSP models are, how they are built, and how they can be applied. You will also be introduced to Rosa’s Model Qualification Method (MQM), a systematic approach for ensuring that a model is fit for the purpose for which it is intended. Concepts will be illustrated with examples and case studies.  Interactive discussions will cover topics including:

  • Criteria for mechanistic physiological QSP modeling projects to ensure impact
  • Planning and scoping the model
  • Incorporating multiple types of evidence and data sources
  • Using “Virtual Patients” to explore uncertainty and variability
  • Relevant qualitative and quantitative model testing
  • Identifying opportunities for mechanistic physiological QSP modeling

The goal of this workshop is to help participants understand how to apply mechanistic physiological QSP modeling research in a drug development context. This is specifically designed to give participants insight into the model development process, the data requirements, best practices, and most suitable applications of modeling techniques.

This workshop will enable participants to articulate the nature and utility of mechanistic physiological QSP models to management and drug development teams and identify opportunities for integrating QSP modeling into the drug development process in their organization.

10:30 - 15:20
Systems Pharmacology: Science and Non-Science? And so What?

Intro text.

  • The role of QSP in the scientific process and common applications
  • Qualification of QSP models and key aspects of QSP organization adoption


Post Conference Workshops
Wednesday 19th February, 2014

12:00 - 13:00